Butylene Glycol, Hexylene Glycol, Ethoxydiglycol, and Dipropylene Glycol are viscous liquids used in the cosmetic industry as humectants, emulsifiers, plasticizers, and solvents. Due to its versatile nature, Bio-based propylene glycol is safe, not considered a carcinogen or endocrine disrupter, and what you'll find in clean skin care products. ATSDR can also tell you the location of occupational and environmental health clinics. ethylene glycol, several factors will determine It is a defining ingredient in the product because it is an essential component of a nourishing base, evenly distributing ingredients, and providing a luxurious texture. Propylene glycol is considered generally safe by the FDA. Excess creatinine is a sign that the kidney is unable to process compounds at a normal rate. amount released to break down. What ages hair? (13) Again, this is an example of the rare (but possible) effects of the accumulation of propylene glycol in your system. Chamblee, GA 30341-3717 hj@_>A;?BpPJ%fQ%h q"]tmE=s{Q!(&,P)21nBFlkipj&ApO'Y::?~N><1KM5|I1dRa6JI:2c> ;9xnSsIlbJ8s",!.%"WBCRCC!:N[ N endstream endobj 54 0 obj <>stream Propylene glycol is safe for consumption, and the FDA approves its use in food at certain concentrations. Propylene glycol can also travel from certain types Many of the food products containing propylene glycol dont have propolyne glycol-free options unless theyre homemade. bloodstream. It is not necessary for your skin to come into contact with them. (Plus Top Benefits and Uses for Skin), Flaxseed Benefits for the Whole Body and How to Add Them to Your Diet, The Worst Halloween Candy & Why You Cant Stop Eating It, L-Glutamine Benefits Leaky Gut & Metabolism, 9 Proven Black Seed Oil Benefits that Boost Your Health, Apple Cider Vinegar Benefits for Weight Loss, Skin Health, Cholesterol & More, Chia Seeds Benefits: The Omega-3, Protein-Packed Superfood. solutions. Up to 600 ppm: (APF = 10) Any supplied-air respirator. According to EWGs Skin Deep database on personal care products, the products are not rated very highly for cleaning applications, but they are rated very highly for cleaning applications. The independent Cosmetic Ingredient Review panel has ruled dipropylene glycol is safe as used in cosmetics. Propylene glycol (1, 2-propanediol) is an organic compound (a diol alcohol) and is a tasteless, odorless and colorless clear oily liquid. Class IIIA Combustible Liquid: Fl.P. DPG is a water soluble, medium viscosity, hygroscopic liquid with a low vapor pressure. Acts as a thickening agent: Guanche notes that DPG acts as a thickening agent that can help protect and strengthen the hair shaft. Up to 600 ppm: (APF = 10) Any supplied-air respirator(APF = 50) Any self-contained breathing apparatus with a full facepiece, Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus, Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister having an N100, R100, or P100 filter. inhalation, skin absorption, ingestion, skin and/or eye contact, irritation eyes, nose, throat; lassitude (weakness, exhaustion), dizziness, headache, Eyes, respiratory system, central nervous system, Centers for Disease Control and Prevention. By clicking the Accept button below, you are consenting to receive and store cookies from our site. When a chemical is released from a large source, Note that the numbers in parentheses (1, 2, etc.) These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. effects. It is used widely in pharmaceuticals, food, cosmetics and even anti-freeze. and state of health. Propylene glycol is generally considered to be a food additive. at or above 140F and below 200F. A 2007 study from the University of Connecticut assessed the treatment of propylene glycol toxicity and also noted it can be dangerous for those with liver problems. Propylene glycol is used as a food additive and in many pharmaceuticals, cosmetics, and industrial applications. The Food and Drug Administration (FDA), in atoxicological profile,has deemed propylene glycol as generally recognized as safe., In the Centers for Disease Control and Preventions exhaustive report of the effects and possible toxicity of propylene glycol, no major health concerns were found. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. Our team includes licensed nutritionists and dietitians, certified health education specialists, as well as certified strength and conditioning specialists, personal trainers and corrective exercise specialists. glycol are primarily responsible for the releases into They are made of a substance. I did mention earlier that propylene glycol is not considered bioaccumulative (builds up over time in the bloodstream). So, although propylene glycol may not be as terrifying as some people claim, it does have enough red flags to cause me to recommend avoiding it. There is no doubt that propyl glycol is a safe ingredient, not only for cosmetics, but also for food and pharmaceuticals. Rare cases suggest severe allergy to propylene glycol that could eventually (but unlikely) lead to death. Dipropylene Glycol has limited direct skin care benefits so its not the best, but its not a bad ingredient either. come into contact with the chemical. Its certainly less dangerous than, for example. 2022 Dr. Axe. After discontinuing the drug that poisoned her body, her condition stabilized for a period of time, but she later died after her condition deteriorated again. propylene glycol is 25 mg of propylene glycol for show that if you have repeated eye, skin, nasal, or A 2007 study from the University of Connecticut assessed the treatment of propylene glycol toxicity and also noted it can be dangerous for those with liver problems. Make use of it! (1) Another name for it is propane-1,2-diol, which is sometimes used when listing it as a compound on ingredient labels. Propylene glycol is also used to This Dr. Axe content is medically reviewed or fact checked to ensure factually accurate information. [Skin irritation caused by propylene glycols]. As the clean beauty movement moves full speed ahead, more and more consumers are interested in product labels and making sure everything they put on their skin and body is safe to use. recipe. classified propylene glycol as "generally recognized These cookies may also be used for advertising purposes by these third parties. smoke products may also be used by private A few years ago, scientists discovered how to synthesize a plant-derived product called propylene Glycol that is used by CORPUS. symptoms. The key difference between dipropylene several days to a week) in surface water and in soil. And with its excellent stability, solvency, and coupling performance. (APF = 50) Any self-contained breathing apparatus with a full facepiece. (7) Generally, creatinine (a product of muscle breakdown and growth) remains in consistent levels in the bloodstream. ( 1) It absorbs water and maintains moisture in food products, medications, cosmetics, and skincare products. Other names for propylene glycol are 1,2-dihydroxypropane, Another place you will find itis in many medications, serving as a way to help your body absorb chemicals more efficiently. However, studies have shown that propylene glycol can be irritating to the skin and scalp . Several common foods containingthis compoundinclude: Most natural alternatives to propylene glycol involve choosing foods and cosmetics free of the substance. That doesnt necessarily quell concerns, however. While the conditions under which these studies occurred areunlikely to be repeated in humans, this information is still relevant. When propylene glycol is used in antifreeze products in place of ethylene glycol, its considered non-toxic antifreeze.. and mists for fire safety training, theatrical Propylene glycol age, sex, nutritional status, family traits, lifestyle, The body of research surrounding this substance is considered fair, according to the Environmental Working Groups assessment. With strict editorial sourcing guidelines, we only link to academic research institutions, reputable media sites and, when research is available, medically peer-reviewed studies. SRS Aromatics. So the question becomes whether PG is inhaled in safe or unsafe volumes by vapers. The CIR Expert Panel evaluated the scientific data and concluded that Butylene Glycol, Hexylene Glycol, Ethoxydiglycol and Dipropylene Glycol are safe for use in cosmetics and personal 7.00 - 199.00. Consumers were amazed and frustrated to hear that their favorite foods and drinks might contain the chemical, exacerbated by its presence in so many other daily products. So, although propylene glycol may not be as terrifying as some people claim, it does have enough red flags to cause me to recommend avoiding it. 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There are a great deal of clean household products available, both commercially or ofthe DIY variety, and they will help you to greatly reduce your chemical exposure. Lets take a look at the current research and potential effects of propylene glycol. The effects of exposure to any hazardous substance depend on the dose, the duration, how you are exposed, personal traits and habits, and whether other chemicals are present. Before the completed growth of these enzyme pathways, parents should avoid allowing their children to ingest or be exposed to many chemicals that are potentially harmful, and pregnant mothers should do the same. Again, this information reflects available research. a solvent for food colors and flavors, and in the For more information, call the ATSDR Information Center at 1-800-232-4636. your liver from damage done by the common headache medication, Prospective mothers are usually very cautious during and after. soil. According to the FDA (Food and Drug Administration), it is used as an additive that is generally safe to add in food. aircraft de-icing agent. chemical, food, and pharmaceutical industries as an You can also use. Propylene glycol breaks down at the same rate as will take between 24 and 50 hours for half the h Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. However, critically ill adults may be an exception to this rule. Regulatory Information SARA 302 Components: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302. called a release, does not always lead to exposure. 4770 Buford Highway glycerine and alcohols are not naturally occurring, whereas glycols exist only in plants. Yes, propylene glycol can go bad. It is usually stored in dark glass bottles and can last for years. But, if left exposed to sunlight, it can turn yellowish and smell bad. To avoid this problem, store it in a refrigerator. Propylene Glycol is used in cosmetics because it helps moisturize skin and hair. A synthetic liquid substance that absorbs water, propylene glycol classified by the chemical formula C3H8O2. (2) The mix-up apparently occurred when the company sent the North American formula instead of the European formula, which contains six times less propylene glycol. These are designed Plant-based versions of propylene glycol have largely been adopted in the cosmetics and pharmaceutical industries due to their superior performance and safety. Lotions and baby wipes also make the list of products that commonly contain this chemical. ethylene glycol, although it does not form harmful According to the World Health People who work in industries that use propylene Annually we request that you confirm your account is valid and verify your email address to protect you and our interests. See: Propylene Glycol Propylene glycol increases your skins propensity to absorb whatever it comes into contact with. One typical adverse reaction to propylene glycol includes mild skin irritation, including causing redness. In most cases, an emulsifier like propylene glycol is used to help blend ingredients in a formula. Waste streams from the manufacture of propylene No large bodies of research exist about the safety of propylene glycol for humans. Usually, thishappens in people who are allergic to the chemical and subsides after a short period of time after the body has had time to break down the compound. also used to create artificial smoke or fog used in DIPROPYLENE GLYCOL Safety Data Sheet according to Federal Register / Vol. Bio-based propylene glycol is a safe, non-cancer-causing substance that is used in a variety of skin care products. Material Safety Data Sheet or SDS for Dipropylene glycol monomethyl ether 818533 from MilliporeSigma for download or viewing in the browser. People with liver or kidney problems, the elderly, pregnant or nursing mothers, and their infants should attempt to limit their exposure to propylene glycol. Propylene glycol is clear, colorless, slightly syrupy Propylene glycol is practically odorless and Quick View Add to Cart. Ethylene glycol, also known as ethylene glycol, is a known carcinogen, endocrine disrupter, allergen, and toxin. citizens. Excess creatinine is a sign that the kidney is unable to process compounds at a normal rate. Items in your cart might be affected by address change. through your skin if you come in direct contact with (. ) Dipropylene glycol is a chemical compound that is commonly used as a solvent or antifreeze. However, what, Propylene glycol (often referred to as PG) is the third product in a chemical process beginning with, , a byproduct of fossil fuel (oil refining and natural gas processing) and also found in nature as a byproduct of fermentation. Ethylene glycol is a known Another place you will find itis in many medications, serving as a way to help your body absorb chemicals more efficiently. Trade Name : Dipropylene Glycol FG ( DPG FG ) Molecular formula : C6H14O3 CAS No: 25265-71-8 EC ( EINECS ) No: 246-770-3 1.2 Relevant identified uses of the substance or mixture and uses advised against: 1.2.1 Recommended Use As a humectant, safe solvent and emulsifier, carrier in products below - cosmetic and personal care - fragrance Dipropylene glycol, which is derived from the production of propylene glycol byproduct, occurs as a byproduct of the production process of polypropyl oxide. and you don't have to worry about over-doing it. They help us to know which pages are the most and least popular and see how visitors move around the site. Dow's DPG is utilized as a solvent, coupling agent and chemical intermediate in numerous industries, having a wide range of practical applications. However, feel free to use some of the recipes on my website to create homemade salad dressings and guilt-free (and chemical-free) desserts. You can also use raw butter instead of margarine for an immediate health booster to your cooking. However, what exactly does that mean? Its unlikely that you will experience any major adverse reactions to propylene glycol through normal exposure from food or cosmetics. It is a clear, colorless, and viscous liquid with a faintly sweet odor. Propylene glycol is considered generally safe by the FDA. paint and plastics industries. How might I be exposed to propylene glycol? If you have questions or concerns, please contact your community or state health or environmental quality department or: For more information, contact: For more information about our use of cookies, please view our Privacy Policy. duration (how long), the route or pathway by which Read on to get all the details on dipropylene glycol, below. Adobe PDF Library 10.1 This ingredients score is higher if used in products that are inhalable (e.g., sprays, powders) because of respiratory concerns. What recommendations has the federal government made to protect human health? (11), The one area in which the CDCs toxicity profile negatively assessed propylene glycol was in the area of neurological symptoms. This website uses cookies to provide you the best experience. In rats, some scientists have found enlarged cells in the respiratory tract, as well as some nasal hemorrhaging. exposed, and your individual characteristics such as ,sN5H. and overall chemical exposure, there are a few ways to avoid propylene glycol when possible. large amounts in the air. Related: What Is Caprylyl Glycol? amounts are not generally considered harmful. ngx-pagination install Coconut Water Dipropylene glycol is a chemical compound that is commonly used as a solvent or antifreeze. We've updated our Privacy Policy, which will go in to effect on September 1, 2022. It is one in a series of Public Health Statements about hazardous substances and their health effects. found there any sort of extensive human-based research on itssafety. While some research states that neonates (preterm infants) have been found to have no adverse side effects from propylene glycol, its also true that infants cannot break down this compound as quickly as an adult can. It is insoluble in water but miscible with most organic solvents. guidelines for propylene glycol. And Im not the only one. It's not necessarily a selling point in haircare products though. Propylene glycol is used by the products that contains it. Propylene oxide is considered a probable carcinogen. Finally, through a. process (separating molecules by the addition of water), you getpropylene glycol. Although this chemical compound is not generally found in nature, it seems to be potentially safe. Bio-based propylene glycol is safe, not considered a carcinogen or endocrine disrupter, and what you'll find in clean skin care products. Perhaps the most concerning part of constant propylene glycol exposure is the way that it may provide other chemicals a free pass into your bloodstream. as a drum or bottle, it enters the environment as a detect. Quick View Options. CDC twenty four seven. Itratespropylene glycol a 3 on itshealth concerns scale, meaning the hazard it presents is moderately low. If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance. This emission, which is also CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. 1,2-propanediol, methyl glycol, The majority of the safety and toxicity information presented is for propylene glycol (PG). In cosmetics, it is used in concentrations as low as .004% to as high as 50% in some perfumes. the air, water, and soil. Improves product texture: Dipropylene glycol can help thin out a product texture to give it a more silky, sleek feeling. You might have heard of DPG's friend propylene glycol and are wondering if there is a difference. These artificial If you eat products that Since ingredients do not have to appear on cosmetic products, you should purchase only from companies who list all ingredients on their packaging and dont include propylene glycol on that list. Risks to human health and the environment from Diropylene Glycol are considered low or negligible when it is properly handled. (3) It(correctly) designates the known issues with propylene glycol to be in the allergies and immunotoxicity category, with no hazard related to cancer or reproductive processes. used to absorb extra water and maintain moisture in whether harmful health effects will occur and what When taken orally and tested by patch test to find the amount of the chemical still in their system, a number of people were found to have varying degrees of neurological issues, including stupor, convulsions and other unspecified severe mental symptoms., In a cat-based study, cats receiving the high dose developed decreased activity, mental depression, and slight to moderate ataxia.. application/pdf make up the National Priorities List (NPL) and are You must accept before you can continue. The liquid in room temperature is clear, colorless, and slightly syrupy, but it is also colorless and colorless. Many people are extremely concerned by the presence of an ingredient in antifreeze (one thats used to deice airplanes, no less) in their food, which has sparked uproar in recent years, especially when three European countries pulled a popular alcoholic drink off the shelves for an, The body of research surrounding this substance is considered fair, according to the Environmental Working Groups assessment. A co-product from the manufacture of monopropylene glycol, with a purity of greater than 99%. heated or briskly shaken to produce a vapor. Bio-based propylene glycol is a safe, non-cancer-causing substance that is used in a variety of skin care products. are clickable links to medically peer-reviewed studies. It is not likely to exist in There is also FDA approval for adding propylene glycol as a food additive. And Im not the only one. Since propylene glycol breaks down Many people became scared of the association between antifreeze and food, although propylene glycol simply lowers the freezing point of water (just like salt) and was only introduced into antifreeze products to replace a more dangerous chemical. What Is Methylisothiazolinone and Why Is It In My Shampoo? oral exposures to propylene glycol for a short time, or inhaling mists from spraying them. Your account has a credit block in place. It is a clear, colorless, and viscous liquid with a faintly sweet odor. It can also enter your bloodstream Other common personal care items on that list might include: When you look at a list of foods containing propylene glycol, youll notice that many of them arent really great for you to begin with. We request that you confirm your account is needed. crystals when it breaks down. Error occurred during login. Division of Toxicology and Human Health Sciences Dobos explains, "The Cosmetic Ingredient Review's expert panel made up of medical professionals, toxicologists, and other scientists determine DPG is safe in their review of extensive data about the use of DPG at concentrations of up to 50% in cosmetics and determined. In another case, the horse mentioned above who suffered myocardial edema eventually died of respiratory arrest.